Piperazine derivatives and its citrate salts are generally used to prepare veterinary drugs to help pigs or poultry including hens and other Ascaris species. This drug is generally available in powder form and easily soluble in water to make it easy to consume for animals. The amount of drugs depends on severity of disease as explained by experts. If Piperazine citrate salts are not consumed in right quantity then chances of healing reduce largely. For pigs or poultry, successive dosage must be given for two regular days and treatment may continue for next 14 days or more.
If we talk about oral administration for human then I am absorbed quickly by the human body and excreted through urine. Based on administration and continuous inspection by experts, for the first 24 hours more than 40 percent of the drug is excreted through urine. The excretion is usually completed in two phases. Firs cycle is completed in the initial 6 hours and the next cycle is completed in rest 18 hours. Similarly, it is absorbed rapidly by hens or pigs and seems highly effective too. The recovery rate by administration team was observed more than 85 percent within first 24 hours only.
Acute toxic studies were also made by experts or different Piperazine derivatives like Piperazine citrate or Piperazine adipate and its different salts. Different salts get hydrolyzed quickly to prepare a wide range of Piperazine variants and level of toxic elements decrease significantly. The drugs may have different results on different animal species. When it is given in right quantity then chances of damages are less and consumer is less susceptible to any adverse affect.
The amount of drug may depend on sex, height, severity of disease and overall weight of affected species. You are not able to identify correct dosage so it is better to take help from experts to avoid extreme conditions. There are cases when consumer dies as well but it was result of improper dose and not the drug itself. According to administration group, level of dose is increased or decreased as per the requirement but it does not remain same throughout the administration period. Effect of piperazine derivatives is also depends on direct animal tolerance where extra dosage may result into excessive vomiting, diarrhea or anxiety etc.
When we talk about the human then chances of adverse affects are rare and it results in case of overdose most of the times. Human may also suffer from nausea, diarrhea, anxiety or vomiting from time to time. These affects are mostly related to children less than 6 years whose body does not overdose of any type of drug. The above study by an administration team makes sure that Piperazine derivatives like Piperazine citrate or Piperazine adipate and its different salts have no serious side effects but it would be great to consume this drug under supervision of health expert only.